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Keep track of Closely (1)omaveloxolone will decrease the level or result of ergotamine by impacting hepatic/intestinal enzyme CYP3A4 metabolism.ergotamine will raise the level or result of ruxolitinib topical by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Slight/Importance Not known.mitotane decreases amounts of ergotamine by impacting h